Our vet had recommended the higher dosage Zylkene for our 13 year old Setter who developed anxiety with the addition of our new puppy. We enjoyed excellent results with her. I ordered the lower dosage product for the puppy as he was extremely hyper, but it yielded no results whatsoever. Giving the product the benefit of the doubt, I will now try the higher dose which I have re-ordered for the old girl, on the pup as his weight has now increased, and see will this make a difference.